Wound Care and Healing

Wound care: the role of advanced wound healing technologies.

Wound repair and regeneration is a highly complex combination of matrix destruction and reorganization. While major hurdles remain, advances over the past generation have improved the clinician's armamentarium in the medical and surgical management of this problem. The purpose of this manuscript is to review the current literature regarding the pragmatic use of three of the most commonly employ...

Biology and Biomarkers for Wound Healing WOUND HEALING

www.PRSJournal.com 18S Wound healing is a multifaceted process governed by sequential yet overlapping phases, including hemostasis, inflammation, proliferation, and remodeling. This process is executed through communication between the various local skin compartments, supporting extracellular matrix, and systemic contributors. Under physiological conditions in a healthy individual, the process ...

Wound care: Patch could improve healing and reduce scarring

Oxygen and Wound Healing

Oxygen is essential to several critical mechanisms in wound healing, including bacterial killing, angiogenesis, fibroplasia, and epithelialization. As a substrate, oxygen provides the respiratory burst necessary for white blood cells to kill engulfed bacteria, hastening resolution of inflammation so that a preliminary matrix can be formed for subsequent fibroplasia and epithelialization. Additi...

Platelets and wound healing.

Platelets help prevent blood loss at sites of vascular injury. To do this, they adhere, aggregate and form a procoagulant surface favoring thrombin generation and fibrin formation. In addition, platelets express and release substances that promote tissue repair and influence processes such as angiogenesis, inflammation and the immune response. They contain large secretable pools of biologically...